Tara McIntosh
Tara McIntosh
Honours Research

Extracting Gene Networks - Rule and Pattern Based Approaches

I developed new Association Rule (AR) mining algorithms to extract gene relationships from microarray data. Existing microarray data mining techniques suffer from two major weaknesses -- restricting the number of genes which can be included in the analysis, and the assumption that only common gene relationships are of interest. My research rectified these. More specifically, I developed the first comprehensive AR algorithm, MaxConf, which can mine dense data with no support threshold (traditionally used to prune uncommon relationships), by incorporating new confidence threshold properties.


Publications

Tara McIntosh Honours Thesis, June 2005 - pdf

Tara McIntosh and Sanjay Chawla. High Confidence Rule Mining for Microarray Analysis. IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 4, no. 4, pages 611-623, Oct-Dec, 2007.

Tara McIntosh and Sanjay Chawla. On discovery of maximal confident rules without support pruning in microarray data. In 5th ACM SIGKDD Workshop on Data Mining in Bioinformatics (BIOKDD '05), Chicago, IL, 2005.